Journal of Indian Society of Periodontology

REVIEW ARTICLE
Year
: 2015  |  Volume : 19  |  Issue : 1  |  Page : 11--13

Sclerostin and occlusion: A brief review


Pankaj Bansal1, Pritma Singh1, Afshan Bey2, Narinder Dev Gupta2 
1 Department of Periodontics, Dr. Z A Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
2 Department of Periodontics and Community Dentistry, Dr. Z A Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Correspondence Address:
Pritma Singh
C/O D.N. Dubey, Near Kalyan Singh Kothi, Marris Road, Aligarh, Uttar Pradesh
India

In its pursuit of understanding the wonders of human body, mankind has stumbled upon yet another discovery which not only is a key to chest of unanswered queries but also opens a plethora of new possibilities. Till recently the osteocytes were considered latent cells merely entrapped in the matrix of bone. With the discovery of beta-catenin pathway and sclerostin molecule, these cells are now being recognized to perform a multitude of physiological functions which are important to bone function and turnover. Mechanosensor function of osteocytes via sclerostin molecule offers new possibilities in alveolar bone preservation. Sclerostin and its inhibitors have potential in prosthetic, regenerative and preventive therapy in dentistry. Osteocytic pathway of sclerostin release and mechanism of its interaction with occlusion is discussed in this article.


How to cite this article:
Bansal P, Singh P, Bey A, Gupta ND. Sclerostin and occlusion: A brief review.J Indian Soc Periodontol 2015;19:11-13


How to cite this URL:
Bansal P, Singh P, Bey A, Gupta ND. Sclerostin and occlusion: A brief review. J Indian Soc Periodontol [serial online] 2015 [cited 2022 Jun 28 ];19:11-13
Available from: https://www.jisponline.com/article.asp?issn=0972-124X;year=2015;volume=19;issue=1;spage=11;epage=13;aulast=Bansal;type=0