Journal of Indian Society of Periodontology

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 16  |  Issue : 4  |  Page : 492--497

Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients


Tie-Lou Chen1, Bing Xu2, Jing-Chang Liu3, Shu-Guang Li1, De-Yi Li4, Guo-chuan Gong3, Zhi-Fen Wu5, Shi-Long Lin3, Yi-Jun Zhou5 
1 Department of Periodontology, Diagnosis and Treatment Center of Stomatological Diseases of CPLA, Shanghai, China
2 Department of Chemistry, Tongji University, Shanghai, China
3 Department of Hyperbaric Medicine and Physiology, Naval Medical Research Institute, Shanghai, China
4 Department of Periodontology, Stomatological Medical College, Shanghai Jiaotong University, Shanghai, China
5 Department of Periodontology, Stomatological Medical College, Fourth Military Medical University, Xi an, China

Correspondence Address:
Tie-Lou Chen
Department of Periodontology, Diagnosis and Treatment Center of Stomatological Diseases of CPLA, Hospital 411 of CPLA. No. 15, Dong Jiang Wan Road, 200081, Shanghai
China

Objective: To investigate the effects of hyperbaric oxygen (HBO 2 ) on aggressive periodontitis (AgP), and subgingival obligate anaerobes in Chinese patients. Materials and Methods: Sixty cases of Chinese patients with AgP were randomly divided into two groups -the HBO 2 group (30 cases) and the control group (30 cases). Study teeth were divided into four groups -: the HBO 2 therapy, the HBO 2 + scaling scaling group, the scaling group and the control group. Subgingival anaerobic organisms were measured with anaerobic culture, and number of obligate anaerobes and facultative anaerobes and Bacteroides melaninogenicus was counted. Comparisons of changes in the clinical indices, and subgingival anaerobes were made between the groups. Results: Highly significant differences in gingival index (GI), probing depth (PD), attachment loss (AL), and Plaque index (PLI), and tooth odontoseisis (TO) were seen in the HBO 2 , the HBO 2 + scaling and the scaling groups when compared with the control group (P<0.01). The number of subgingival anaerobes as well as the types of obligate anaerobes and facultative anaerobes and the number of Bacteroides melaninogenicus were reduced markedly in these three treatment groups. Highly statistical differences in clinical indices, subgingival anaerobe number and types of obligate anaerobes and facultative anaerobes and Bacteroides melaninogenicus were found when comparisons were made between the HBO 2 + scaling and the HBO 2 groups, as well as between the HBO 2 + scaling and the scaling groups. Clinical follow-ups indicated that the GI, PD, AL, TO, PLI and subgingival anaerobes number of the three therapeutic groups were reduced more severely than the control group. Conclusions: HBO 2 had good therapeutic effects on Chinese patients with AgP. HBO 2 therapy combined with scaling and root planing was the most beneficial in the treatment of AgP. The therapeutic effect of HBO 2 on AgP is most likely through inhibition of the growth of subgingival anaerobes. Clinical follow-ups suggest that the effect could last more than 2 years.


How to cite this article:
Chen TL, Xu B, Liu JC, Li SG, Li DY, Gong Gc, Wu ZF, Lin SL, Zhou YJ. Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients.J Indian Soc Periodontol 2012;16:492-497


How to cite this URL:
Chen TL, Xu B, Liu JC, Li SG, Li DY, Gong Gc, Wu ZF, Lin SL, Zhou YJ. Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients. J Indian Soc Periodontol [serial online] 2012 [cited 2021 Jul 30 ];16:492-497
Available from: https://www.jisponline.com/article.asp?issn=0972-124X;year=2012;volume=16;issue=4;spage=492;epage=497;aulast=Chen;type=0