Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2014  |  Volume : 18  |  Issue : 2  |  Page : 229-231

Periodontal considerations in a patient with glucose-6-phosphate dehydrogenase deficiency with associated pancytopenia: A rare case report

Department of Periodontology, Government Dental College and Hospital, Amritsar, Punjab, India

Correspondence Address:
Harinder Gupta
31 North Avenue, Street No. 2, Bhadson Road, Patiala, Punjab - 147 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-124X.131334

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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme defect in humans. G6PD deficiency is widely distributed in tropical and subtropical parts of the world and a conservative estimate is that at least 500 million people have a G6PD deficient gene. In several of these areas, the frequency of a G6PD deficiency gene may be as high as 20% or more. The vast majority of people with G6PD deficiency remain clinically asymptomatic throughout their lifetime. However, all of them have an increased risk of developing neonatal jaundice and a risk of developing acute hemolytic anemia when challenged by a number of oxidative agents. The most important treatment measure is prevention: Avoidance of the drugs and foods that cause hemolysis.

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