| CASE REPORT |
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| Year : 2014 | Volume
: 18
| Issue : 2 | Page : 229-231 |
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Periodontal considerations in a patient with glucose-6-phosphate dehydrogenase deficiency with associated pancytopenia: A rare case report
Harinder Gupta, Ruchika Arora, Monika Kamboj
Department of Periodontology, Government Dental College and Hospital, Amritsar, Punjab, India
Correspondence Address:
Harinder Gupta
31 North Avenue, Street No. 2, Bhadson Road, Patiala, Punjab - 147 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-124X.131334
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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme defect in humans. G6PD deficiency is widely distributed in tropical and subtropical parts of the world and a conservative estimate is that at least 500 million people have a G6PD deficient gene. In several of these areas, the frequency of a G6PD deficiency gene may be as high as 20% or more. The vast majority of people with G6PD deficiency remain clinically asymptomatic throughout their lifetime. However, all of them have an increased risk of developing neonatal jaundice and a risk of developing acute hemolytic anemia when challenged by a number of oxidative agents. The most important treatment measure is prevention: Avoidance of the drugs and foods that cause hemolysis. |
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