Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2014  |  Volume : 18  |  Issue : 2  |  Page : 226-228

Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni

1 GSBS Medical Trust, Loni, Maharashtra, India
2 Department of Periodontology, Rural Dental College, Loni, India
3 Private Practitioner, Loni, Maharashtra, India
4 Hiranandani Hospital, Thane, Maharashtra, India
5 Late Shri Yashwantrao Chavan Memorial Medical and Rural Development Foundation's Dental College, Maharashtra, India
6 BVP Dental College, Navi Mumbai, Maharashtra, India

Correspondence Address:
Avneesh Tejnani
Gods Gift, 103, Prof. Almeida Park, TPS IV, 9th Road, Bandra (W), Mumbai - 400 050, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-124X.131332

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Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. Materials and Methods: Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug. Results: The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions. Conclusions: In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.

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