Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2012  |  Volume : 16  |  Issue : 4  |  Page : 588-591

Gingival pemphigus vulgaris preceding cutaneous lesion: A rare case report

Department of Periodontics, Armed Forces Medical College, Pune, India

Correspondence Address:
Saroj K Rath
Department of Periodontics, Armed Forces Medical College, Pune - 411 040
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-124X.106922

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Pemphigus is a group of autoimmune diseases characterized by formation of intraepithelial bullae in skin and the mucous membrane. Pemphigus vulgaris affects the oral mucosa in nearly all cases. Pemphigus vulgaris is characterized by auto antibodies directed against desmosome-associated protein antigens (desmoglein-3) found in epithelial and epidermal intercellular substance. We report here a case of pemphigus vulgaris of gingiva in an adult female patient at an early stage followed by dermatologic involvement. Perilesional incision was taken and histopathological and direct immunofluorescence was done for identification of specific antibodies. The oral lesions were treated with 0.1% Triamcinolone acetonide ointment and Prednisolone 20 mg twice daily with multivitamins was administered systemically for skin lesion.

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