Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
Home | About JISP | Search | Accepted articles | Online Early | Current Issue | Archives | Instructions | SubmissionSubscribeLogin 
Users Online: 1096  Home Print this page Email this page Small font size Default font size Increase font sizeWide layoutNarrow layoutFull screen layout
Year : 2008  |  Volume : 12  |  Issue : 1  |  Page : 8-15

Comparitive effects of tetracyclines and citric acid on dentin root surface of periodontally involved human teeth: A scanning electron microscope study

Department of Periodontics, M.S. Ramaiah Dental College and Hospital, Bangalore - 560 054, India

Correspondence Address:
Bhavya Shetty
Department of Periodontics, M.S. Ramaiah Dental College and Hospital, Bangalore - 560054
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-124X.44090

Clinical trial registration None

Rights and Permissions

Periodontal diseases produce physical and chemical alterations in the root cementum. Various topical applications as root conditioning agents have been recommended as an adjunct to mechanical root surface debridement to remove smear layer, endotoxins and to expose collagen fibers on dentin surface. The objectives were to compare dentin surface changes following applications of tetracyclines and citric acid to the instrumented root surface of periodontally involved human teeth under scanning electron microscope. The study group comprised of 80 dentin samples, which were prepared from periodontally-compromised teeth, planned for extraction. Diseased surfaces were root planed. The teeth were sectioned and solutions of tetracycline HCl, minocycline, doxycycline and citric acid were applied to the surfaces with cotton pellets for 5minutes.The root surface samples were then examined by scanning electron microscope. Removal of smear layer in all the four groups was near total except a few areas. All four groups showed slight difference in mean number of total dentinal tubules. Minocycline and doxycycline showed no significant difference. The proportion of patent dentinal tubules was (74%) in tetracycline HCl group compared to minocycline (48.3%), doxycycline 42%), citric acid (52%), showing the differences statistically significant. Tetracycline group showed higher number of patent tubules when compared to minocycline, doxycycline and the difference was statistically significant. Results of this study suggest that tetracycline is the best current tetracycline form for root surface conditioning as measured by its ability to affect both dentin smear layer removal and tubule exposure.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded789    
    Comments [Add]    
    Cited by others 12    

Recommend this journal