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2008| September-December | Volume 12 | Issue 3
November 15, 2008
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The challenge of antioxidants to free radicals in periodontitis
Gowri Pendyala, Biju Thomas, Suchetha Kumari
September-December 2008, 12(3):79-83
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection. Patients with periodontal disease display increased PMN number and activity. This proliferation results in high degree of free radical release culminating in heightened oxidative damage to gingival tissues, periodontal ligament and alveolar bone. Damage mediated by free radicals can be mitigated by "ANTIOXIDANT DEFENSE SYSTEM ". Physiological alteration and pathological states produced by free radicals depend on disequilibrium between free radical production and antioxidant levels leading to oxidative stress. Hence this study has been designed to estimate the TOTAL ANTIOXIDANT CAPACITY in patients with PERIODONTITIS and healthy control subjects
Clinical and histological evaluation of alloderm GBR and BioOss in the treatment of Siebert's class I ridge deficiency
Sabitha Sudarsan, KV Arun, MS Priya, Ramya Arun
September-December 2008, 12(3):73-78
Complete prosthetic rehabilitation using implants require the presence of adequate dimensions of alveolar bone. Ridge augmentation procedures include the use of guided bone regeneration (GBR) procedures where the barrier membrane provides cell occlusion and space for the regenerating tissues. Alloderm GBR has been introduced for the purpose of augmenting bone and has been postulated to have the additionally ability to integrate into soft tissues. Twenty-two patients with Siebert's class I ridge deficiency were treated with BioOss and Alloderm GBR and followed up for a period of nine months. Significant increase in ridge dimensions of both hard and soft tissues were observed at six months period itself, suggesting that it as an effective method of augmenting deficient ridges.
Application of ultrasound in periodontics: Part II
Vivek K Bains, Ranjana Mohan, Rhythm Bains
September-December 2008, 12(3):55-61
Ultrasound offers great potential in development of a noninvasive periodontal assessment tool that would offer great yield real time information, regarding clinical features such as pocket depth, attachment level, tissue thickness, histological change, calculus, bone morphology, as well as evaluation of tooth structure for fracture cracks. In therapeutics, ultrasonic instrumentation is proven effective and efficient in treating periodontal disease. When used properly, ultrasound-based instrument is kind to the soft tissues, require less healing time, and are less tiring for the operator. Microultrasonic instruments have been developed with the aim of improving root-surface debridement. The dye/paper method of mapping ultrasound fields demonstrated cavitational activity in an ultrasonic cleaning bath. Piezosurgery resulted in more favorable osseous repair and remodeling in comparison with carbide and diamond burs. The effect of ultrasound is not limited to fracture healing, but that bone healing after osteotomy or osteodistraction could be stimulated as well.
Evidence-based periodontal therapy: An overview
R Vijayalakshmi, V Anitha, T Ramakrishnan, Uma Sudhakar
September-December 2008, 12(3):62-66
Dentists need to make clinical decisions based on limited scientific evidence. In clinical practice, a clinician must weigh a myriad of evidences every day. The goal of evidence-based dentistry is to help practitioners provide their patients with optimal care. This is achieved by integrating sound research evidence with personal clinical expertise and patient values to determine the best course of treatment. Periodontology has a rich background of research and scholarship. Therefore, efficient use of this wealth of research data needs to be a part of periodontal practice. Evidence-based periodontology aims to facilitate such an approach and it offers a bridge from science to clinical practice. The clinician must integrate the evidence with patient preference, scientific knowledge, and personal experience. Most important, it allows us to care for our patients. Therefore, evidence-based periodontology is a tool to support decision-making and integrating the best evidence available with clinical practice.
from dental plaque: A microbiological study
Uma Sudhakar, CN Anusuya, T Ramakrishnan, R Vijayalakshmi
September-December 2008, 12(3):67-72
The aim of our study was to isolate
from dental plaque in gastric and duodenal ulcer patients and compare it with dental plaque of healthy subjects.
Materials and Methods:
Fifty patients in the age range of 25-50 years who were endoscopically proven cases of duodenal and gastric ulcer were chosen.
was isolated from the dental plaque of these patients using culture method and rapid urease test (RUT). It was compared with the dental plaque from control group (25 students). The specificity and sensitivity of RUT was compared with culture method. The oral hygiene index (OHI) score and plaque index were assessed.
Ten percent positivity was observed in the study group by culture. Though RUT showed 70% positive isolation it is neither a specific test nor a conclusive test as compared to culture. The result correlates with oral hygiene in study population.
Further, more studies are needed to compare RUT and culture, with serology and polymerase chain reactions. The ability to detect
from dental plaque using these methods offer the potential for the noninvasive test for infection and would aid in support of oral transmission of
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