Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2019  |  Volume : 23  |  Issue : 4  |  Page : 345-350

Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation

1 Departments of Periodontics, PDM Dental College and Research Institute, Bahadurgarh, Haryana, India
2 Consultant Periodontist, Karnal, Haryana, India

Correspondence Address:
Dr Anshu Blaggana
Department of Periodontics, PDM Dental College and Research Institute, Sector – 3A, Sarai Aurangabad, Bahadurgarh - 124 507, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jisp.jisp_688_18

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Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3rd and 5th day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5th day. Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group. Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.

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