Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
Home | About JISP | Search | Accepted articles | Online Early | Current Issue | Archives | Instructions | SubmissionSubscribeLogin 
Users Online: 272  Home Print this page Email this page Small font size Default font size Increase font sizeWide layoutNarrow layoutFull screen layout
Year : 2018  |  Volume : 22  |  Issue : 6  |  Page : 480-486

Comparison of gingival crevicular fluid periostin levels in healthy, chronic periodontitis, and aggressive periodontitis

Department of Periodontics, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India

Correspondence Address:
Dr. Fazal Ilahi Jamesha
Department of Periodontics, Sri Ramakrishna Dental College and Hospital, SNR College Road, Coimbatore - 641 006, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jisp.jisp_266_18

Rights and Permissions

Background: In both states of health and disease, the integrity of connective tissue along with regulation in formation of bones are well maintained by periostin (POSTN) which is a matricellular protein secreted by fibroblasts. The present study aimed to assess the gingival crevicular fluid (GCF) POSTN levels in patients with chronic periodontitis (CP) and aggressive periodontitis and to compare them with that of healthy controls. Materials and Methods: A total of 39 individuals were recruited and allocated into the healthy group, and two periodontitis groups (the chronic and the aggressive types) (13 in each group). The samples of GCF fluid were collected using microcapillary pipette. The POSTN levels were estimated using the enzyme-linked immunosorbent assay. Results: The mean levels of total POSTN in GCF fluid (in pg/μl) were 182.41, 79.87, and 49.28 for the healthy, CP, aggressive periodontitis groups, respectively. There was a statistically significant difference between the groups with P < 0.05. Furthermore, there were statistically significant differences when compared among the groups with P < 0.05. When all three groups were examined together, there were negative correlations between GCF POSTN levels and clinical parameters. Conclusion: The GCF POSTN levels reduced with an increase in the severity of the periodontitis. With the present study results, we could conclude that the GCF POSTN level can be considered as a dependable marker in periodontal disease diagnosis, disease activity, and healing.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded227    
    Comments [Add]    

Recommend this journal