Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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CASE REPORT
Year : 2017  |  Volume : 21  |  Issue : 5  |  Page : 409-411

Drug-induced atypical hyperplasia enveloping salivary gland malignancy


1 Department of Oral Pathology, Postgraduate Institute of Dental Sciences, Rohtak, Haryana, India
2 Department of Oral Surgery, Postgraduate Institute of Dental Sciences, Rohtak, Haryana, India
3 Department of Periodontics, Postgraduate Institute of Dental Sciences, Rohtak, Haryana, India

Correspondence Address:
Anjali Narwal
Department of Oral Pathology, Pt. B. D Sharma University of Health Sciences, Postgraduate Institute of Dental Sciences, Rohtak, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jisp.jisp_456_15

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Gingival enlargement is a very common side effect associated with the administration of several drugs, mainly anticonvulsants, calcium channel blockers (CCBs), and immunosuppressants. Amlodipine (a CCB) is a safe antihypertensive drug with a longer duration of action. Gingival enlargement induced by amlodipine is less prevalent among CCBs. Since the pathogenesis is not well understood, it is still a challenge for clinicians to diagnose and manage cases effectively. This case presents an atypical unilateral palatal gingival enlargement in a 61-year-old hypertensive female taking amlodipine. Difficulty for a pathologist in diagnosing in spite of repeated sample submission from the lesion and repeated failure for the operator to reach the underlying pathology due to amlodipine-induced hyperplasia have also been discussed in this case report.


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