Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
Home | About JISP | Search | Accepted articles | Online Early | Current Issue | Archives | Instructions | SubmissionSubscribeLogin 
Users Online: 1361  Home Print this page Email this page Small font size Default font size Increase font sizeWide layoutNarrow layoutFull screen layout
ORIGINAL ARTICLE
Year : 2014  |  Volume : 18  |  Issue : 1  |  Page : 53-58

To estimate salivary aspartate aminotransferase levels in chronic gingivitis and chronic periodontitis patients prior to and following non-surgical periodontal therapy: A clinico-biochemical study


Department of Periodontics and Implantology, Jaipur Dental College, Jaipur, Rajasthan, India

Correspondence Address:
Praveen Kudva
Department of Periodontics and Implantology, Jaipur Dental College, Tehsil Amer, Village Dhand, Jaipur, Rajasthan
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-124X.128209

Rights and Permissions

Context: Saliva can be used as a diagnostic fluid in dentistry. Various enzymes have been proposed as markers for periodontal destruction. One of them is aspartate aminotransferase, for which salivary analysis can offer a cost-effective approach for monitoring the disease. Changes in enzymatic activity reflect metabolic changes in the gingiva and periodontium in inflammation. Aims: The purpose of this study was to assess the aspartate aminotransferase levels in saliva prior to and following scaling and root planning (SRP) at 1 month and 3 month interval and correlating it with the clinical parameters in generalized chronic gingivitis and chronic periodontitis patients. Materials and Methods: Thirty patients with generalized chronic gingivitis and 30 with generalized chronic periodontitis were selected. The activity of aspartate aminotransferase levels in saliva were assessed biochemically before and after SRP at 1 month and 3 months. The aspartate aminotransferase levels were correlated with clinical parameters (gingival index and probing depth). Statistical Analysis Used: A paired t test was done. Results: A decrease in gingival index, probing depth, and aspartate aminotransferase levels were seen in both the groups at 1 and 3 months which was found to be statistically highly significant (P value 0.00). Aspartate aminotransferase levels were statistically significantly correlated with the clinical parameters at baseline (P < 0.05) but at 3 months, a positive correlation was seen in both the groups which was statistically insignificant (P > 0.05). Conclusions: Elevated salivary aspartate aminotransferase levels were seen in generalized chronic gingivitis and chronic periodontitis patients, with higher values recorded in generalized chronic periodontitis correlating to the tissue destruction taking place in these conditions.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2574    
    Printed29    
    Emailed0    
    PDF Downloaded418    
    Comments [Add]    
    Cited by others 1    

Recommend this journal