Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2013  |  Volume : 17  |  Issue : 2  |  Page : 182-187

Drug-induced gingival overgrowth: The nemesis of gingiva unravelled


Department of Periodontology, Government Dental College and Hospital, Patiala, Punjab, India

Correspondence Address:
Vipin Bharti
70, Sibia Colony, Opp. Income Tax Office, Patiala - 147 001, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-124X.113066

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Drug-induced gingival overgrowth or enlargement manifests as abnormal growth of the gingiva due to an adverse drug reaction (ADR) in patients treated with anticonvulsants, immunosuppressants, and calcium channel blockers. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. It gradually becomes a source of pain and the condition often leads to disfiguration. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. It would seem pertinent to identify and explore possible risk factors and relating them with the treatment plan. This article throws light on respective drugs and their association with gingival overgrowth and approaches to treatment based on current knowledge and investigative observations.


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