Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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REVIEW ARTICLE
Year : 2011  |  Volume : 15  |  Issue : 4  |  Page : 310-317

Saliva: A diagnostic biomarker of periodontal diseases


1 Department of Periodontology, Tatyasaheb Kore Dental College and Research Centre, Kolhapur, Maharashtra, India
2 Department of Pediatric and Preventive Dentistry, Dr. D.Y. Patil Dental College and Hospital, Maharashtra, India

Correspondence Address:
Priti Basgauda Patil
Department of Periodontology, Tatyasaheb Kore Dental College and Research Centre, New Pargaon - 417 137, Kolhapur, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-124X.92560

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Early detection of disease plays a crucial role in successful therapy. Early diagnosis and management reduces the severity and possible complications of the disease process. To overcome this challenge, medical researchers are devoted to finding molecular disease biomarkers that reveal a hidden lethal threat before the disease becomes complicated. Saliva, an important physiologic fluid, containing a highly complex mixture of substances, is rapidly gaining popularity as a diagnostic tool. Periodontal disease is a chronic disease of the oral cavity comprising a group of inflammatory conditions affecting the supporting structures of the dentition. In the field of periodontology, traditional clinical criteria are often insufficient for determining sites of active disease, for monitoring the response to therapy, or for measuring the degree of susceptibility to future disease progression. Saliva, as a mirror of oral and systemic health, is a valuable source for clinically relevant information because it contains biomarkers specific for the unique physiologic aspects of periodontal diseases. This review highlights the various potentials of saliva as a diagnostic biomarker for periodontal diseases.


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