Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2010  |  Volume : 14  |  Issue : 4  |  Page : 231-235

A comparative study on the efficacy of a commercial fibrin adhesive (Tisseel® ) vis-à-vis silk suture on wound closure following periodontal surgical procedures

Department of Periodontology & Implantology, Priyadarshini Dental College, Pandur, Thiruvallur District, Tamil Nadu, India

Correspondence Address:
A G Manimegalai
Department of Periodontology and Implantology, Priyadrashini Dental College, Pandur, Thiruvallur District, Tamil Nadu - 631 203
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-124X.76925

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Aims and Objectives: To evaluate the efficacy of fibrin adhesive sealant (Tisseel® ), a human biological tissue adhesive, as compared to conventional suture placement in pocket elimination and mucogingival surgical procedures. Materials and Methods: The study sample consisted of 25 patients (10 male and 15 female patients), in the age group of 25-40 years, with localized periodontitis in relation to the anterior region of the maxilla and mandible. They were divided into three surgical groups: Group I, Group II and Group III. Each of these groups was further divided into control and experimental groups. In all the control groups, the flaps/grafts were approximated with 4-0 black braided silk. In the experimental groups, the flaps/grafts were approximated with fibrin adhesive sealant (Tisseel; ). Clinical parameters were taken pre-operatively.operatively and post-operatively on the 1 st , 2 nd , 3 rd , 7 th , and 10 th , day. Results: The Fibrin Adhesive System (FAS) showed superior results in all the parameters measured, i.e., hemostasis, fixation of tissues, reduction in plaque and gingival index and probing depth postoperatively. Conclusion: The results of this study indicate that periodontal surgery using FAS enhances various periodontal regenerative surgical procedures.

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