Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
Home | About JISP | Search | Accepted articles | Online Early | Current Issue | Archives | Instructions | SubmissionSubscribeLogin 
Users Online: 178  Home Print this page Email this page Small font size Default font size Increase font sizeWide layoutNarrow layoutFull screen layout
ORIGINAL ARTICLE
Year : 2008  |  Volume : 12  |  Issue : 1  |  Page : 16-20

Comparative analysis of GCF β-glucuronidase level in diabetic and nondiabetic patients with chronic periodontitis: A clinicobiochemical study


Department of Periodontology and Implantology, Bapuji Dental College and Hospital, Davanagere - 577 004, Karnataka, India

Correspondence Address:
Dhoom Singh Mehta
Department of Periodontology and Implantology Bapuji Dental Colege and Hospital, Davangere 577004, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-124X.44092

Rights and Permissions

Recent evidences prove that, release of potent lysosomal enzymes e.g. β -Glucuronidase by degranulation of polymorponuclear leukocytes in host gingiva may contribute significantly to tissue destruction and the pathogenesis of periodontal disease. The purpose of the present study was to compare and correlate GCF β -Glucuronidase with periodontal status among diabetic and non-diabetic patients with chronic periodontitis. A total number of 75 patients were equally divided into Group I (control group), Group II (non diabetic with chronic periodontitis) and Group III (diabetic with chronic periodontitis). Clinical parameters like Plaque index, Gingival index, Probing Pocket Depth and RBS were recorded. The β -Glucuronidase level in GCF of all three groups was determined by spectrophotometric analysis. It was observed that the periodontitis patients irrespective of their diabetic status, showed increased periodontal destruction with elevated level of β -Glucuronidase than the controls. Also, the diabetic patients showed increased severity of periodontal destruction and the elevated level of β -Glucuronidase, thus indicating diabetics at a higher risk for progressive periodontal destruction.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2606    
    Printed139    
    Emailed1    
    PDF Downloaded471    
    Comments [Add]    
    Cited by others 3    

Recommend this journal